| abstract |
An epitheliocyte growth accelerator containing a hepatocyte growth factor (HGF) as the active ingredient. In the present invention, the HGF may be derived from human tissues, animal tissues, or blood components, or it may be produced by genetic engineering. In this regard, the host cell to be used in the genetic engineering may be selected from among Escherichia coli , Bacillus subtilis , yeasts, filamentous fungi, plant cells and animal cells. The epitheliocyte growth accelerator of the present invention specifically accelerates growth of normal epitheliocytes, and improves cell motility. Therefore, it is pharmaceutically useful for the treatments of injury, dermoulcer, etc. Also, it is useful as a growth agent for hair root cells, and an agent to be added in cosmetics. Since the epitheliocyte growth accelerator of the present invention does not have fibloblast growing activity or canceration accelerating activity, it is highly useful as a pharmaceutical with less sideeffects. |