| abstract |
Biodegradable ortho-ester polymers useful in the preparation of soft biodegradable pharmaceutical compositions such as ointments, creams, gels or the like. A new synthetic process for the preparation of polymers is also planned. The synthesis includes a single phase reaction between a monomeric ortho-ester and a triol. The pharmaceutical compositions are useful for the regulated release of therapeutic agents, and can be administered for several purposes, for example to treat deep wounds, including burns, and to treat periodontitis. |