abstract |
An aqueous paint used to coat a solid substrate to render the surface thereof antithrombogenic comprises an antithrombogenic agent, a non-blood leachable organic polymeric binder and, optionally; a spacer material. Preferably, the aqueous paint contains water, a base, heparin, ethylene acrylic acid copolymer, and colloidal silica. A polymeric resin substrate can be sulfonated prior to coating and/or a coated substrate can be treated with a non-blood leachable bonding agent, especially glutaraldehyde. |