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filingDate 1991-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_babd5bf86ed09155ff647be1ec4dab8b
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publicationDate 1992-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0481351-A2
titleOfInvention Process for the preparation of 2-pyrrolidones
abstract R 1 und R 2 unabhängig voneinander Wasserstoff, C 1 - bis C 2 o-Alkyl, oder gegebenenfalls durch C 1 - bis C 4 -Alkyl substituiertes C 3 - bis C 8 -Cycloalkyl oder Phenyl bedeuten, ndurch Umsetzung von 3-Cyanopropionsäureester der allgemeinen Formel IIn nin der R 1 und R 2 die obengenannten Bedeutungen haben und R 3 für C 1 - bis C 8 -Alkyl steht, mit Wasserstoff bei erhöhten Temperaturen und erhöhtem Druck, indem man die Umsetzung in Gegenwart von Ammoniak an einem Katalysator, der Cobalt, Mangan und Phosphor enthält, durchführt.Process for the preparation of 2-pyrrolidinones of general formula I. in which the substituents R 1 and R 2 independently of one another are hydrogen, C 1 to C 2 o-alkyl, or C 3 to C 8 cycloalkyl or phenyl optionally substituted by C 1 to C 4 alkyl, by reacting 3-cyanopropionic acid ester of the general formula II in which R 1 and R 2 have the meanings given above and R 3 represents C 1 - to C 8 -alkyl, with hydrogen at elevated temperatures and elevated pressure, by carrying out the reaction in the presence of ammonia over a catalyst, the cobalt, manganese and contains phosphorus.
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