abstract |
Peptides of the formula wherein X is alkanoyl, A is optionally substituted D-Na (2), D-Phe or D-Trp, B is optionally substituted D-Phe, C D-Pal (3) or is optionally substituted D-Phe or D-Trp and D is Tyr or His, E D-Ser (R¹), F Leu, Trp or Phe, G L-Ser (R¹), H Gly-NH₂, D-Ala-NH₂ or Azagly-NH₂ and R¹ mean a glycosyl residue have an inhibitory effect on the formation the gonadotropins lutropin and follitropin and thus also on the synthesis of testosterone and estrogen. A method for producing these peptides is described. |