abstract |
The invention relates to the unique short region Us sequence of the Marek's disease virus encoding the protein kinase. It also relates to recombinant herpes viruses in which a heterologous gene has been inserted into the homologous region of the gene coding for the protein kinase, and in particular the recombinant Marek viruses expressing a gene for an avian pathogen, which may possibly be a d gene. another serotype of Marek virus. It also relates to a process for the preparation of these recombinants, as well as to the vaccines obtained. |