abstract |
Anthracycline glycosides of formula 1:n wherein R 1 is hydrogen or methoxy group; R 2 is hydrogen or hydroxy; both R 3 and R 4 represent hydrogen or one of R 3 and R 4 is hydroxy and the other of R 3 and R 4 a represents hydrogen; R 5 represents hydrogen atom or an acyl residue - COX in which X is a C 1 -C 8 linear or branched alkyl chain, an aryl, an aryl lower alkyl, or a 5-or 6-membered heteroaromatic group are anti-tumour agents. |