http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0474273-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5128cfc84a0fb189fceb3cd240c44493 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7455 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 |
filingDate | 1991-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1996-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfeccad8c8a9c1f2205539ebf9752e26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d23ed0a81457253168e2589e4bfe31f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0507702dbb6a2733127961393ef78b15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ba175f4bc61ea4e996159de45407d19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_405f1604bf40a55fd8c5c3d96df5dc7f |
publicationDate | 1996-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0474273-B1 |
titleOfInvention | A polypeptide capable of interacting with thrombin |
abstract | Disclosed is a substantially pure polypeptide having a specific amino acid sequence containing (a) an amino acid residue selected from the group consisting of Asp, Glu and Gla wherein Gla represents a gamma -carboxyglutamic acid residue or (b) a peptide or polypeptide residue consisting of at least two amino acid residues selected from Asp, Glu and Gla, wherein the above-mentioned at least two amino acid residues are all the same or combinations of the Asp, Glu and Gla. The polypeptide is capable of interacting with thrombin to form a binding therebetween, thereby exhibiting an activity to inhibit the blood coagulation and platelet aggregation by thrombin and/or an activity to promote the thrombin-catalyzed activation of protein C. This novel polypeptide has a low molecular weight so that it is suitable for oral or nasal administration. |
priorityDate | 1990-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 289.