http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0472019-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ec7d5322ffd68cf949a109a06d884d0c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06 |
| filingDate | 1991-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86f10f41cf5ad7b39adec44085a4fce0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbb62b685e0dfc7208e10e28c2dbc860 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb98fb83fe1234f5098a7d95e03240e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3863bd50b9943d3974f0a165d9c8ff99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39adff609ef88f39dfde3d2f8e2e7eb0 |
| publicationDate | 1992-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0472019-A1 |
| titleOfInvention | Process for producing 3'-deoxy-3'-fluorothymidine |
| abstract | This invention provides a process for producing 3'-deoxy-3'-fluorothymidine, which comprises allowing 3'-deoxy-3'-fluoro-5'-mesylthymidine (the stating material) to react with an acetylating agent, selected from the group consisting of alkali metal salts of acetic acid, amine salts of acetic acid and ammonium acetate, in an aprotic, ploar solvent to form the 5'-acetyl derivative, and ammonium acetate, in an aprotic, polar sovent to form the 5'-acetyl derivative, and eliminating the 5'-acetyl group from this intermediate, thereby giving the objective 3'-deoxy-3'-fluorothymidine. n According to the process of this invention described above, the 5'-mesyl derivative can be efficiently acetylated, and 3'-deoxy-3'-fluorotymidine can be obtained in a high yield. |
| priorityDate | 1990-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 131.