http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0471804-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-3513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate | 1991-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2002-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b9a2ec026ef28b7313dfb57fdb19d94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10602e16b6b2158d46a448dcd8b7459c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_524fe88ac796a464c8997833659477e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a76e30fdb7b58aab9ff3a2b200d4866e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90bb23d750dea6b65be0f6852318ad84 |
| publicationDate | 2002-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0471804-B1 |
| titleOfInvention | Novel human cyclin a compositions and their production method, a corresponding nucleotide sequence, a method and agents for detecting or diagnosing cell multiplication, and a method and agents for inhibiting cell multiplication |
| abstract | The invention is directed generally to a DNA sequence coding for human cyclin A and in particular to antibodies, or antisera including such antibodies, which bind to human cyclin A as encoded by the sequence of SEQ ID NO: 1 and which are useful in detecting cellular proliferation. The antibodies of the invention can be polyclonal or monoclonal, and are preferably generated by injection of purified human cyclin A into an animal host. The invention is particularly advantageous because it has been discovered that the gene encoding for human cyclin A is a site for integration of the hepatitis B virus associated with hepatocellular carcinoma, and by detecting human cyclin A through the use of the antibodies of the invention, one can detect and diagnose cell proliferation. Through the use of the present invention, cell proliferation and tumorigenesis can thus be detected at early stages, and such conditions can then be treated or inhibited by the use of anti-sense human cyclin A DNA. |
| priorityDate | 1990-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.