http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0470078-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d269c8e41f178194d858c230c9f85e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 1990-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f580da1524548ba082122724a83fc976 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_025f5ee731b4033ce53d396af7436741 |
| publicationDate | 1992-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0470078-A1 |
| titleOfInvention | 1,4-dihydropyridines |
| abstract | The invention relates to compounds of formula (I), as well as its pharmaceutically acceptable salts, wherein R represents an optionally substituted thienyl, benzothienyl, furyl, benzofuranyl, pyridinyl, quinolinyl or isoquinolinyl group; either R1 and R2 each independently represent H or C1-C6 alkyl; either R1 and R2, taken together with the nitrogen atom to which they are attached, form a pyrrolidinyl, piperidinyl, morpholinyl, piperazinyl, N '- (C1-C4 alkyl) piperazinyl or N' - (C2-C4 alkanoyl) group piperazinyl; R1 represents H or C1-C4 alkyl and R2 represents cyano, C3-C7 cycloalkyl, aryl, heteroaryl, or a C1-C4 alkyl group replaced by at most 2 substituents, independently selected from cycloalkyl, C1-C4 alkoxycarbonyl, aryl and heteroaryl; R3 represents C1-C6 alkyl or aryl (C1-C4) alkyl; R4 represents either (a) a fused imidazolyl, triazolyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, oxazolyl or thiazolyl group, said group being optionally benzo, pyrido, pyridazino, pyrimido or pyrazino fused, or (b) a fused imidazolyl group oxazolo or thiazolo , R4 being optionally replaced by 3 substituents at most selected from C1-C4 alkyl, C1-C4 alkoxy, trifluoromethyl, cyano and halo. The compounds are useful for the curative or prophylactic treatment of allergic, hypersecretory and inflammatory conditions in animals, including humans. |
| priorityDate | 1989-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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