| abstract |
The subject of the invention is pyridazine derivatives of formula: <IMAGE> in which: Ar represents an optionally mono- or disubstituted phenyl group, a pyridyl group or a thienyl group; R3 represents a straight or branched C1-C5 alkyl, a group -CH2-C6H5, a group -CH2-CH2-C6H5; R4 represents the group <IMAGE> in which: X represents a straight or branched C1-C6 alkylene R5 and R6 each independently represent hydrogen, a C1-C4 alkyl, or constitute with the nitrogen atom to which they are linked, a heterocycle chosen from pyrrolidine, morpholine or piperidine, or else R4 represents a group chosen from: <IMAGE> in which n is as defined above and R7 represents H or C1-C4 alkyl; <IMAGE> in which n is as defined above or <IMAGE> as well as their salts with mineral or organic acids. Application: drugs useful for the treatment of a cholinergic deficit. |