abstract |
Pharmaceutical compositions comprising a drug, an enhancer of absorption at a mucosal surface and a cyclodextrin, process for their preparation and use of a cyclodextrin in the manufacture of a medicament for administration by absorption at a mucosal surface. Cyclodextrins reduce the toxic effects caused by mucosal absorption enhancers. In particular the compositions are useful in relation to delivery of drugs by the intra-nasal route. |