| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-335
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
1991-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_877a4d2c1deb3a3e97cba919d8982008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52da277343dd1c8dbe4a5bf8dd52c64a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6e24f128bd3cd87d39c8d550f9de483
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ee17e1e04e04d62709101c387c736f0 |
| publicationDate |
1991-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0461427-A2 |
| titleOfInvention |
Cyclodextrin complex |
| abstract |
A complex of a fumagillin derivative represented by the general formula:n n wherein R¹ is hydrogen; R² is halogen, N(O)mR⁵R⁶, N⁺R⁵R⁶R⁷ · X⁻, S(O)nR⁵ or S⁺R⁵R⁶ · X⁻ (wherein R⁵, R⁶ and R⁷ are independently an optionally substituted hydrocarbon or heterocyclic group; X⁻ is a counter anion; m is an integer of 0 or 1; n is an integer from 0 to 2; and R⁵ and R⁶ together with the adjacent nitrogen or sulfur atom may form a nitrogen- or sulfur-containing heterocyclic group which may be substituted and form a condensed ring); or R¹ and R² together represent a bond; R³ is 2-methyl-1-propenyl group or isobutyl group; A is O or NR⁸ (wherein R⁸ is hydrogen or an optionally substituted lower alkyl or aryl group); R⁴ is hydrogen, an optionally substituted hydrocarbon group or an optionally substituted acyl group); or a salt thereof, with an optionally etherified cyclodextrin is disclosed. The present invention also provides an antineoplastic agent containing the complex. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2973376-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7087768-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0658342-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100455900-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012130906-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0819430-A1 |
| priorityDate |
1990-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |