| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_692dc75829481c48c017b52f352e2bad |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-23 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02 |
| filingDate |
1990-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1994-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fdb53055a4d044c02e2a734512369ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc97857a66c14758f3a5cda05ecc8855 |
| publicationDate |
1994-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0460065-B1 |
| titleOfInvention |
A process for the generation of proliferating cd4 lymphocytes |
| abstract |
Peripheral blood mononuclear cells (PBMC) or tumor infiltrating lymphocytes (TIL) are treated with a dipeptide alkyl ester such as leucyl leucine methyl ester (LLME) or with an amino acid alkyl ester such as leucine methyl ester (LME) to deplete monocytes and large granular lymphocytes, then cultured in media containing T-cell stimulant and interleukin-2 to generate and proliferate a lymphocyte population enriched in CD4<+> lymphocytes. |
| priorityDate |
1989-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |