http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0457834-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a93aa938a621af353cc038e4368ceab |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 |
| filingDate | 1990-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_294234b95ca913c8eee51017033b0a17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3abba62b2902c4f0db4ef3402e6acb30 |
| publicationDate | 1991-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0457834-A1 |
| titleOfInvention | SPREAD RELEASE DOSAGE FORM. |
| abstract | Described are a multi-phase injectable spread release system and a method for treating humans and other mammals with this system. Said system comprises a regulated and prolonged diffusion of a micro-encapsulated macromolecular bioactive agent of biological origin, said bioactive agent being encapsulated in microcapsules of bioerodible encapsulation polymer, which allows a spread and multiphase release of said agent, namely (i) a first part of said bioactive agent which, upon injection, is capable of being released from said microcapsules made of bioerodible polymer, in a manner in which only a relatively small amount of said agent is released during said first phase, the initial biological reaction being minimized due to the fact that said part produces a mild reaction similar to that normally observed with low doses of conventional administration; and (ii) secondary parts of said bioactive agent which provide a significantly higher level of bioactive agent in doses capable of causing a serious reaction in the patient, in the absence of the prior release of said first part. |
| priorityDate | 1989-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.