| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate |
1991-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ec3215fd80308ef6c59e352aeaa5e1a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfe1f89342193fd2f6aeed955d2bc10d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8850a3e9e774931613dd778cb31d21e3 |
| publicationDate |
1991-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0455423-A2 |
| titleOfInvention |
Ortho-lithiation process for the synthesis of 2-substituted 1-(tetrazol-5-yl) benzenes |
| abstract |
A process utilizes the tetrazole functional group to direct lithiation at the ortho position of a phenyltetrazole and generate a nucleophilic aryllithium species which then undergoes reaction with an electrophile to generate a 2-substituted 1-(tetrazol-5-yl)benzene. The process is useful in the production of intermediates in the synthesis of angiotensin II antagonists. This novel process is a more cost effective and versatile route for the large-scale preparation of these key intermediates. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2696745-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0782996-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006134078-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0643704-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100354802-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0643704-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1384717-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1384717-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0782996-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0540356-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0540356-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5965738-A |
| priorityDate |
1990-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |