Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-48 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C325-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F15-06 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-753 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-733 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 |
filingDate |
1991-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc629b2287551ad28f725117cfce7ec3 |
publicationDate |
1991-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0454146-A1 |
titleOfInvention |
Cytotoxic bicyclo[7.3.1] tridec-4-ene-2,6-diyne compounds and process for the preparation thereof |
abstract |
The present invention relates to a novel and efficient process for the preparation of 8-hydroxy-bicyclo[7.3.1]-tridec-4-ene-2,6-diyne ring system which is part of the aglycone of esperemicin and to novel cytotoxic agents having said bicyclic ring system. The present invention also provides a method for treating animal malignant tumors by administering to an animal in need of such treatment an antitumor effective amount of a compound having the formula |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0538898-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0538898-A3 |
priorityDate |
1990-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |