| abstract |
A compound having the formula I:n n in which X is a group of formula:n n in which R₁ is NHR₄ in which R₄ is H, acyl, alkoxycarbonyl or acyl, R₂ is arylene, heteroarylene, alkenylene, CH₂, O or NH, or any conbination of these, R₃ is H, NH₂ or NH-acyl, in the R- or S- configuration, and m and n are each O or an integer from 1 to 5; Y is a group of formula:n n in which y is an integer ranging from 1 to 12; Z is NH₂ or the radical of any of the common alpha-amino acids, or of the amides of such amino acids; and pharmacologically - compatible salts of the compound of formula I; provided that, when Y is Gly, X is other than Lys. The compounds of formula I are useful as platelet aggregation inhibitor. |