| abstract |
An isochromane derivative having the general formula In n in which each of R₁, R₂, and R₃ is one to four substituents independently selected from hydrogen, hydroxy, alkyl (1-4 C), alkoxy (1-4 C), halogen, or CF₃, or represents a methylenedioxy group; nR₄ is selected from hydrogen or alkyl (1-4 C); nAlk is an alkylene group with 1-4 carbon atoms; nAlk' is an alkylene group with 2-4 carbon atoms, when R₅ is selected from hydrogen or alkyl (1-4 C) and X is O or S; or nAlk' is an alkylene group with 1-4 carbon atoms or a bond, when R₅ is an alkyl (1-4 C) group and X is CH₂ or a bond; nor a pharmaceutically acceptable salt thereof. |