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filingDate 1991-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1996-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2df9ba9414a6a4a2127b20526206f6eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcae9f80e074521e5168b58cbce9bd87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52aa1ad91ff32d7c5d9c9f628fd5392d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5eb42ae3454e8d7a35b909aa7ab634f
publicationDate 1996-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0448243-B1
titleOfInvention Milbemycin ether derivatives, their preparation and their therapeutic and agrochemical uses
abstract Milbemycin ether derivs. of formula (I), and their salts and esters, are new. R1 is 4-8C cycloalkyl, R (substd. by 3-8C cycloalkyl which is itself opt. subtd. by Q) or a gp. of formula (i): R2 is e.g H, halo, CN, NO2, R (opt. substd. by Q') RO, 2-6C alkoxyalkyl, TH, TCOR4, TCOCOR4, TCHR6NHCOR6 etc.; T is (CH2)nNR9 (bonded to the ring via C); n is 0, 1 or 2; m is 1 or 2; each R6 is e.g, H, A (opt. substd. by Q''), 2-8C aliphatic hydrocarbyl (contg. one or two double or triple bonds), 3-8C cycloalkyl (opt. subtd. by Q), or 6-14C aryl, or NR6R6 is a 3-7 membered heterocycle (opt. contg. 1 other O, S or N heteroatom); or NR6NR6 is a 3-7 membered heterocycle (opt. contg. 1 other O, S or N hetroatoms, R is R, 3-7C cycloalkyl, or R(substd. by 1-3 6-10C aryl which ar themselves opt. substd. by Q); R9 is H or R; R is 1-4 alkyl; A is 1-8C alkyl; V is CH2, CH2CH2 or OCH2; R5 is Me, Et, iPr or sec-Bu; X is OH, 1-5C alkenoyloxy (opt. substd. by Q''') or hydroxyimino; Q is e.g, halo, RO, R, RS, 1-5C alkanoyloxy, ROCO, CN, NO2, NHR, N(R)2, CONH2 etc.; Q is halo, RO, RS or 1-5C alkaneyloxy; Q'' is e.g, 3-8C cycloalkyl, RO, RS, 2-5C cyanoalkylthio, ROCO, halo, CN, NO2, NH2 etc.; Q''' is halo, RO, ROCO or COOH.
priorityDate 1990-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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