| abstract |
The invention relates to a compound of formula (I), in which R1 and R2 are independently selected from hydrogen, lower alkyl, cycloalkyl, lower alkenyl, adamantyl, aryl, substituted aryl, heterocyclic group , substituted alkyl, substituted amide, functionalized carbonyl and a nitrogen-containing ring in which R1, R2 and the adjacent nitrogen atom form a ring; R11 represents hydrogen, lower alkyl or lower alkenyl; R20 represents hydrogen, lower alkyl or lower alkenyl; B represents - (CH2) m-, a substituted alkenylene, -QCH2- where Q represents O, S, NH or a substituted amino, -CH2Q- where Q is as defined above or B represents NH; Z represents C = O, S (O) 2, or C = S; Ar is a heterocyclic group, aryl or substituted aryl; D is a substituted or unsubstituted oxindol-3-yl, indolin-3-yl or indol-3-yl; and m is between 0 and 4; or a pharmaceutically acceptable salt of this compound. |