http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0441833-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa48a431ce250933eb0fdd7a1caf3f30 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B09B2101-68 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B09B3-0075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7084 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 |
| filingDate | 1989-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c4baff5bb88e63eb075a5b4390eaee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c79bd57d8309ce1e940f73d65a6e7c6 |
| publicationDate | 1991-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0441833-A1 |
| titleOfInvention | DOSAGE FORM TO AVOID ABUSE. |
| abstract | Pharmaceutical compositions and forms for administering substances liable to misuse; these compositions and forms make the abuse more difficult without reducing the beneficial therapeutic effects of the substance susceptible to abuse. The topical compositions (1) contain: (a) the substance liable to be used improperly (3) in a form which is permeable to the skin or mucous membrane; and (b) an antagonist (4) of said substance in a form which is not permeable to the skin or mucosa to which the composition is to be applied. Controlled flow pharmaceutical forms (10) which release the substance susceptible to misuse (13) contained in a drug reservoir composition (11) arranged behind a barrier (16) for controlling the rate of release, contain the said substance (13) in a form which can be released by the pharmaceutical form (10), and the antagonist (14) in a form which cannot be released by the pharmaceutical form. This invention makes it possible to administer a substance liable to misuse according to the method prescribed in large doses while limiting the risks of abuse of the compositions and pharmaceutical forms inherent in the other methods of administration. The transdermal forms recommended for this invention use fentanyl as a substance susceptible to abuse and naltrexone as an antagonist. |
| priorityDate | 1988-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.