http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0440483-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_700ff9a01db2075489cb7ed87392dc28 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 |
| filingDate | 1991-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2003-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5472872cd6bff9530f86a256af1617c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4eb6ec442437af709008464a5696de6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dcfa5151047260c7a45080612dd832b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77eb9688d009da9d787f7c27b83a2dbb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b03017c0e33d65b8a2fcf21785d9e89 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e74623667fb4c664ebff3dd4c7b05039 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e0082aba78ec6380598499c74ff5912 |
| publicationDate | 2003-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0440483-B2 |
| titleOfInvention | Process for purifying immune serum globulins |
| abstract | A multi-step process for purifying an immune serum globulin fraction from a crude plasma protein fraction involves precipitating non-serum globulin proteins from an aqueous suspension of the crude plasma protein fraction using a protein precipitant, adding a virus-inactivating agent to the clarified immune serum globulin-containing liquid, absorbing the immune serum globulins onto a cation exchange resin and washing non-serum globulin contaminants from the resin, subjecting the eluate to ultrafiltration to concentrate the immune serum globulins and separate them from low molecular weight species, contacting the concentrate with an anion exchange resin to absorb non-serum globulin contaminants, passing the immune-serum globulins through the anion exchange resin under conditions that leave non-serum globulin contaminants bound to the resin, and subjecting the filtrate to a molecular washing step to produce a purified immune serum globulin fraction. This process results in products substantially free of active viruses and contaminating lipids, activated complements and low molecular weight peptides. In addition, the process is advantageous in terms of efficiency and adaptability to large-scale production. |
| priorityDate | 1990-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.