| abstract |
An enzyme which acts on a peptide C-terminal/glycine adduct of formula (I), (wherein A represents a residue formed by removing an α-amino or imino group and an α-carboxyl group from a natural α-amino acid, and X represents a hydrogen atom or a residue of an amino acid derivative which combines with the N atom via a carbonyl group) to produce a peptide C-terminal/α-hydroxyglycine adduct of formula (II), (wherein A and X are each as defined above), and another enzyme which acts on the compound of formula (II) to produce a C-terminal amidated peptide of formula (III), wherein A and X are each as defined above. |