| abstract |
A naproxen formulation for oral administration on a once-daily basis comprises a first portion of the naproxen formulated in a multi-particulate pellet form designed to release the drug at a rate sufficient to maintain therapeutically effective blood levels substantially over 24 hours when administered each day on a once-daily basis and, optionally, a second portion of the naproxen formulated so as to release the drug promptly following administration so as to obtain a relatively immediate therapeutic response. |