| abstract |
The invention relates to a renin inhibiting compound having the formula (I), wherein A is a substituent; R1 represents hydrogen, lower alkyl, substituted lower alkyl or lower alkenyl; X represents CH2, CHOH, C (O), O, S, S (O), SO2, NH, N (O) or -P (O) O-; R3 represents lower alkyl, lower alkenyl or substituted lower alkyl; and T is a mimicry of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof. |