| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae8e5779487c4df97e162c57f01b2cf0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a333e6344b62fb21a7c1ee592b165fca |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-92 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-045
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
| filingDate |
1991-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9013a23908ae35903e8bea7a42796872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45257acd271c69b4e0d5c1aab75c0b2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8ce75f8c585cd1d1c91d0ff0f5133ac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66534d8ab6f6ba79078fe85ffa98fa33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5d69832e1121432e441e855efb3ff70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71cd67222682592d1029ffce14fb2700 |
| publicationDate |
1991-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0436502-A2 |
| titleOfInvention |
Novel glucose isomerases with an altered pH optimum |
| abstract |
A method for selecting amino acid residues is disclosed which upon replacement will give rise to an enzyme with an altered pH optimum. The method is specific for metalloenzymes which are inactivated at low pH due to the dissociation of the metal ions. The method is based on altering the pK a of the metal coordinating ligands or altering the K ass for the metal binding. New glucose isomerases with an altered pH optimum are provided according to this method. These altered properties enable starch degradation to be performed at lower pH values. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7883408-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7918455-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7382229-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5266475-A |
| priorityDate |
1990-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |