| abstract |
The present invention concerns neutral sugar derivatives (Formula I) of pradimicins, their use as antifungal agents, methods for their preparation, and intermediates for their synthesis.n wherein R¹ is selected from the group consisting of H, methyl, and hydroxymethyl, and when R¹ is methyl or hydroxymethyl, the resulting amino acid residue has the D -configuration; and R² is H or ß- D -xylosyl with the proviso that, when R¹ is methyl, R² is H; or a pharmaceutically acceptable salt thereof. |