abstract |
A novel phenylethylene derivative of the formula:n n wherein R¹ is phenyl group, a fluorophenyl group, a methoxyphenyl group, thienyl group, furyl group, oxopyrrolidinyl group or pyridyl group, or a pharmaceutically acceptable ester, amide, lactone or salt, which has excellent HMG-CoA reductase inhibitory activity and is useful as an anti-hyperlipidemic agent, a pharmaceutical composition containing the same, and processes for preparing the same as well as an intermediate therefor. |