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filingDate 1990-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c4f2ac1c41bbaea5e1f980069a75a4e
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publicationDate 1991-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0429360-A2
titleOfInvention Inhibition of withdrawal syndrome
abstract n peut avoir les valeurs 1 à 6, et R représente un atome d'hydrogène, un halogène, un radical alkyle inférieur en C₁ à C₄, un radical nitro, un radical hydroxy, un radical oxo, un radical alcoxy inférieur en C₁ à C₄, un radical cyano, un radical carboxylate d'alkyle inferieur en C₁ à C₄, un radical aryle ou aryle substitué, un radical amino ou amino substitué, de formule n dans laquellen R₁ et R₂, identiques ou différents, représentent un atome d'hydrogène, un radical alkyle, un radical aryle, un radical alkylcarboxy, un radical arylcarboxy, un radical alkylsulfonyle ou un radical arylsulfonyle, les fragments alkyle de ces radicaux contenant de 1 à 4 atomes de carbone npour la fabrication de médicaments destinés au traitement des troubles associés au syndrome d'abstinence induit par la suppression de benzodiazépines telles que le Diazépam, de la cocaïne, de l'alcool et/ou de la nicotine. The present invention relates to the use of derivatives of general formula I in which: n can have the values 1 to 6, and R represents a hydrogen atom, a halogen, a lower C₁ to C₄ alkyl radical, a nitro radical, a hydroxy radical, an oxo radical, a lower C₁ to C₄ alkoxy radical, a cyano radical, a carboxylate radical of lower C₁ to C₄ alkyl, an aryl or substituted aryl radical, an amino or substituted amino radical, of formula in which R₁ and R₂, identical or different, represent a hydrogen atom, an alkyl radical, an aryl radical, an alkylcarboxy radical, an arylcarboxy radical, an alkylsulfonyl radical or an arylsulfonyl radical, the alkyl fragments of these radicals containing from 1 to 4 carbon atoms for the manufacture of medicaments intended for the treatment of disorders associated with abstinence syndrome induced by the suppression of benzodiazepines such as Diazepam, cocaine, alcohol and / or nicotine.
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