Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1e7af8847969b90f35bb949bd09f73f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C327-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-532 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-44 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-46 |
filingDate |
1989-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1995-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96f176a6878588be0fddfe9cc7b76307 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32f3c6663f39342d223242c78363bdbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad35b508d7331f2370efab94fc247679 |
publicationDate |
1995-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0428534-B1 |
titleOfInvention |
Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom |
abstract |
This invention discloses heterobifunctional coupling agents for making a wide array of molecular conjugates. The agents contain a sterically hindered thiol, linked through a spacer arm to a second group reactive toward nucleophiles such as 1 DEG and 2 DEG amines or reactive thiols that are present on biological and organic materials. The coupling agents are useful for making conjugates containing a sterically hindered linkage. |
priorityDate |
1988-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |