abstract |
The present invention concerns the construction of solid phase assembly of biopolymers through assembly of shorter biopolymer sequences, for example, assembly of genes from oligonucleotides, polypeptides from oligopeptides, and polysaccharides from oligosaccharides. The present invention also relates to the remodeling, or reconstruction of biopolymers, wherein a section of the biopolymer sequence is excised, then replaced by a modified segment. |