| abstract |
There are disclosed condensed purine derivatives represented by formula: <CHEM> alkyl or benzyl; each of X<1> and X<2> independently represents hydrogen, lower alkyl, aralkyl or phenyl; and n is an integer of 0 or 1; R<1> represents hydrogen, lower alkyl, alicyclic alkyl, noradamantan-3-yl, dicyclopropylmethyl or styryl; and R<2> represents hydrogen, lower alkyl or alicyclic alkyl; or a pharmaceutically acceptable salt thereof. The derivatives and pharmaceutically acceptable salts are useful as diuretics, renal protecting agents, antiallergic agents and hypotensives. |