abstract |
The glycosaminoglycan salts (heparin, its fractions or fragments `` supersulfated '', dermatan sulfate, heparan sulfate, modified heparins) with cations of formula (I) in which R1, R2, R3 and R4 represent for example H , alkyl, cycloalkyl; R5 and R6 represent H, alkyl or aryl; R7 and R8 represent H or alkyl; n and m in the range from 1 to 4 while X = -O-CO-O-; -O-CO-; -NH-CO-; -NH-CO-NH- etc., present the pharmacological properties typical of glycosaminoglycans themselves also by oral or rectal administration. |