| abstract |
This invention relates to N-hydroxy-dibenz[b,e]oxepinalkylamines, N-hydroxy-dibenz[b,e]oxepinalkanoic acid amides and related heterocyclic analogues of the formulan where X together with the carbon atoms to which it is attached forms a benzene or thiophene ring; W and Z are independently hydrogen, halogen, loweralkyl, or trifluoromethyl, R¹ is hydrogen, loweralkyl, or acyl; R² is hydrogen, loweralkyl, cycloalkyl, arylloweralkyl or acyl; m is 0 or 1 and n is an integer of 0 to 12 and the pharmaceutically acceptable salts thereof. The compounds of this invention exhibit dermatological and analgesic activity. |