http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0418341-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d3a63854c7a1afe23086eebce835f46 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-703 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 |
| filingDate | 1990-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb8e29947d32551749415afee0967f63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc26d9cd2dd60e6717d7d440bd533a8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b698b2ca2513b4ee09cff82d65655efc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18068f9b90de2595ecf1ec8ce7fb6719 |
| publicationDate | 1991-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0418341-A1 |
| titleOfInvention | Percutaneous drug delivery system |
| abstract | Method for releasing a drug through the skin of an animal, which comprises applying an enzyme preparation to a localized region of the skin for a predetermined period of time, in an amount sufficient to alter the structure of the localized region of the skin ; closing this localized region of the skin with occlusion means (20) during this predetermined time interval; removing this means of occlusion (20) and applying an effective amount of the drug to the localized region of the skin. The invention further relates to a percutaneous drug delivery system, comprising contacting means (30) for contacting an enzyme preparation with a localized region of the skin; it also relates to an occlusion means for closing this localized region of the skin brought into contact with this contact means (30); and means (32) for applying a medicament to said localized region of the skin after the contacting means and the occluding means have been removed therefrom; this means of contacting and this means of applying the medicament are different parts (30, 32). The invention also relates to a method for delivering a drug through the skin of an animal, which comprises applying a percutaneous penetration stimulator, comprising effective amounts of a combination of enzymatic and non-enzymatic penetration stimulators, to a localized region of the skin of this animal for a predetermined period of time, in an amount sufficient to make this localized region of the skin more permeable to the drug; closing the localized region of the skin with occlusion means (20) during this predetermined time interval; removing this occlusion means (20); and applying an effective amount of the drug to this localized region of the skin so that at least a portion of the drug penetrates through the skin. |
| priorityDate | 1989-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 341.