| abstract |
The compounds of the formula wherein A, R¹, R², R³, R⁴, R⁵, R⁶, R⁷ and R⁸ have the meaning given in claim 1, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates and pharmaceutically acceptable salts thereof inhibit the action of the natural enzyme renin and can therefore be used in the form of pharmaceutical preparations for combating or preventing high blood pressure and heart failure. They can be produced by various processes known per se. |