abstract |
4-(2-Methyl-2-hydroxypropylamino)-5,6-dihydrothieno[2,3-b]thiopyran-2- sulfon a mide-7,7-dioxide is a major mammalian metabolite of 4-(2-methylpropylamino)-5,6-dihydrothieno[2,3-b]thiopyran-2-sulfonamid e-7,7-diox ide and is itself an active carbonic anhydrase inhibitor useful in the treatment of ocular hypertension by topical administration. |