| abstract |
Bi-aromatic esters.n n n The esters correspond to the formula: in which: R₁ represents H, OH, _CH₃, -CH₂OH, -CH (OH) CH₃, -COOR₉, or SO₂R₁₀, R₉ represents H, C₁-C₆ alkyl or a mono or polyhydroxyalkyl radical, R₁₀ representing OH, C₁-C₆ or r ′ and r˝ representing H, C₁-C₆ alkyl, aryl, aralkyl, mono or polyhydroxyalkyl, or r ′ and r˝ taken together form a heterocycle, R₂ represent H, C₁-C₆ alkyl, OR₉, F or -CF₃, R₃ , R₄ and R₅ represent H, F, OH, -CH₃, -OCH₃, -CF₃, -COOH or -CH₂OH, R₆ and R₈ represent H, C₃-C₁₅ α-substituted alkyl C₄-C₁₂ α-α dis disubstituted cycloalkyl C₃ -C₁₂, C₅-C₁₂mono or polycyclic cycloalkyl in which the bonding carbon is trisubstituted, -SR₁₁, -SO₂R₁₁ or -SOR₁₁. R₁₁ representing C₁-C₆ alkyl or cycloalkyl, R₆ and R₈ cannot simultaneously represent H, R₇ represents H, C₁-C₆ alkyl, alkenyl, alkenyloxy, OR₁₂ or SR₁₃, R₁₂ representing H, C₁-C₆ alkyl, or alkenyl, R₁₃ representing H, C₁-C₆ alkyl or aralkyl, provided that when R₁ represents -CH₂OH, -CH (OH) CH₃, -COOR₉ or and R₂ represents H then: (i) either R₃ and R₄ are different from H or -CH₃, (ii) either R₇ is different from the radical OR₁₂ and R₆ or R₈ is cycloalkyl> C₇, (iii) either R₇ represents OR₁₂, but R₆ and R₈ are then different from H, (iv) either R₇ represents OR₁₂, but then R₅ is different from H.n n n Use in human and veterinary medicine and in cosmetics. |