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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
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filingDate 1990-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1996-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4120e68945540d1fe58f0cb39abf949b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96591ae8a39d2347dd6d1250303f51da
publicationDate 1996-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0407860-B1
titleOfInvention Lithium salts as red blood cell lysing and hemoglobin denaturing reagents
abstract Use of a lithium salt, particularly lithium thiocyanate, as an agent for lysing red blood cells and denaturing hemoglobin in the performance of an immunoassay to detect the relative amount of a hemoglobin derivative in a blood sample. The method is particularly useful in the determination of hemoglobin A1c. The method provides a rapid means for releasing hemoglobin from red blood cells by lysis and for exposing the epitope that is characteristic of the A1c form. Low concentrations of the lithium salt provide rapid release and denaturation of hemoglobin without the need for dilution prior to the performance of the immunoassay.
priorityDate 1989-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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