| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_03ced34ffeaed1231d8e1819c979d3bf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S436-824
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-044 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
1990-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba0f07a557534be2fac2b5212f5211fe |
| publicationDate |
1991-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0407035-A2 |
| titleOfInvention |
Method for the determination of lipid and/or apoprotein moiety of intact lipoproteins |
| abstract |
Disclosed are methods that permit the determination of both lipid moiety (LM)and apoprotein expressed epitope immunoreactivity (EEI) of intact isolated lipoprotein species. One format of the method isolates a lipoprotein species by means of a ligand binding to a solid phase, and quantitates thereafter the LM and/or the EEI. n A complementary variant format provides for non-quantitative study of a constant number of lipoprotein particles exploring the sizes of the particles scanning the apoprotein epitopes (EEI). n Disclosed also is a method using lipid moiety dynamics (LMD) and expressed epitopes immunoreactivity dynamics (EEID) to explore the lipid loading and unloading of the lipoprotein species during a fast-feeding cycle. Both the LMD and EEID of lipoprotein particles may be performed as a panel, individual or in any combination. This can be used to detect abnormalities in lipid metabolism that precede the hyperlipidemias associated with cardiovascular disease. n Disclosed also are kits comprising materials for performing the LMD/EEID determinations. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0767384-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2831959-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5844097-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7098036-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5364793-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6107045-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0722086-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006061646-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03038435-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006061655-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5583201-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0722086-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5770452-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9600903-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0531933-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008523377-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008523379-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2005313125-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-710945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0531933-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1022567-A1 |
| priorityDate |
1989-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |