| abstract |
Compounds of structuren in which A is a pyridyl ring; R 1 and R 2 are the same, or different and are each hydrogen, C 1-4 alkyl, -(CH 2 )- n Ar in which n is 0 to 4 and Ar is an optionally substituted phenyl group, or R' and R 2 together with the nitrogen atom to which they are attached form a saturated or unsaturated ring optionally containing one or more further heteroatoms; R 3 and R 4 are the same or different and are each hydrogen, C 1-4 alkyl, (CH 2 ) n Ar 1 in which n is 0 to 4 and Ar' is an optionally substituted phenyl group, or R 3 and R 4 together with the nitrogen atom to which they are attached form a saturated or unsaturated ring optionally containing one or more further heteroatoms; and R 5 is hydrogen or C 1-4 alkyl; processes for their preparation, pharmaceutical compositions containing them and their use in therapy as anti-ulcer agents. |