| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_741b3f48ab49782c52ece3e3c73e3c35 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B31-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 |
| filingDate |
1990-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eecd6e5a0399595b93066a234b4e8a9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edb3c18d14dcabbde69a4b65cad5f038
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_463b2da84c537aec75dcdc999f711d43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c899c00bc36f57eace0cfe4011dd7c32 |
| publicationDate |
1996-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0402724-B1 |
| titleOfInvention |
Hydroxyethyl starch as plasma expander and process for its preparation |
| abstract |
A hydroxyethyl starch for use as plasma expander which is obtainable by hydrolytic predegradation of a starch rich in amylopectin, partial hydroxyethylation to a specific substitution degree in the presence of alkali and subsequent hydrolytic degradation to a specific molecular weight, comprises a mean molecular weight of 60,000-600,000 and a substitution degree MS of 0.15-0.5. The ratio of the substitution of C2 to the substitution of C6 of the anhydroglucose units is 8-20 and the substitution degree DS lies in the range from 0.15 to 0.5. A process for the preparation of this hydroxyethyl starch employs 2-chloroethanol as hydroxyethylation agent. The hydroxyethylation is carried out under alkaline conditions at room temperature, the pH value held at a value of about 12 and the temperature held at a value of about 20 DEG C. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102532330-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1926155-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013113496-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013113747-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7815893-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102532330-A |
| priorityDate |
1989-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |