http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0399839-A3
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 |
| filingDate | 1990-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1992-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0399839-A3 |
| titleOfInvention | Intraocular pressure reducing 15-acyl prostaglandins |
| abstract | The invention provides ophthalmic compositions for nreducing ocular hypertension comprising an nophthalmically acceptable excipient and at least one ncompound of the formula: n n wherein the dotted lines represent a single bond, or a ndouble bond in the cis or trans configuration; A is nOH or a pharmaceutically acceptable salt thereof or nOR₅; R₁ and R₂ combined are -OH/-OH, =O/-OH, or n-OH/=O; R₃ is an acyclic hydrocarbon, saturated or nunsaturated, having from 1 to 20 carbon atoms, or R₃ nis -(CH₂) n R₄ where n is 0-10; R₄ is an aliphatic ring nfrom 3 to 7 carbon atoms or an aromatic or nheteroaromatic ring; and R₅ is an aliphatic radical of nfrom 1 to 10 carbon atoms. n Also provided are novel 15-acyl prostaglandins and a nprocess for the preparation of 15-acyl prostaglandins. |
| priorityDate | 1989-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.