abstract |
A process for producing L-phenylalanine is carried out by culturing a microorganism belonging to the genus Serratia , Escherichia , Pseudomonas , Enterobacter , Salmonella , Erwinia , Proteus , Citrobacter , Paracoccus , Arthriobacter , Bacillus , Brevibacterium , Corynebacterium , Flavobacterium , Klebsiella , Kluyvera or Micrococcus having the ability to convert phenypyruvic acid into L-phenylalanine in the presence of fumaric acid and ammonium ion or urea, in a culture medium containing phenylpyruvic acid, fumaric acid and ammonium ion or urea or causing cells of said microorganism or product of treatment thereof to react on phenylpyruvic acid, fumaric acid and ammonium ion or urea in an aqueous solution; forming L-phenylalanine in the resultant culture broth or aqueous solution; and recovering L-phenylalanine therefrom. |