http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0384842-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4acae202b6a15394281949545e70d2f6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0083 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
filingDate | 1990-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1993-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efa66ab369b76871724ebec216ed7ccb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2a28ba4785053002089a68ecdc3151b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5dd977522f9e6b14fc54f6fd476eb63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_311f64041807fd8013c637c28ccb7baf |
publicationDate | 1993-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0384842-B1 |
titleOfInvention | 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them |
abstract | The invention relates to the compounds (I): n<IMAGE>n in which A and B are either n<IMAGE>n where R2 and R'2 are H or alkyl (C1-4), or n<IMAGE>n where R3 is H or alkyl (C1-4) or acyl, andn - either R17 and R'17 together form a ketone,n - or R17 is hydroxyl or acyloxy and R'17 represents hydrogen, alkyl, alkenyl or alkynyl, these groups being optionally substituted,n - X represents methylene, arylene, CH2-O or arylenoxy,n - Y represents a single bond or aliphatic chain (C1-18) optionally interrupted by one or more arylene(s) or oxygen(s) or optionally oxidised sulphur(s), the chain optionally terminating in an arylene,n - Z represents a single bond or CH2-O, on the understanding that when Y and Z are a single bond, X cannot be methylene or CH2-O,n -RA and RA' represent hydrogen, alkyl optionally substituted with aryl, alkyl or dialkylamino, hydroxyl, halogen or esterified carboxyl, or RA and RA' form, with the nitrogen, a saturated or unsaturated heterocycle optionally containing one or more other hetero atoms and optionally substituted with an alkyl (C1-4), on the understanding that at least one of RA or RA' is not a hydrogen,n to their preparation, to their use as medicaments, to compositions containing them and to the new intermediates obtained. |
priorityDate | 1989-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 540.