http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0384740-A3
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56972 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5052 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569 |
| filingDate | 1990-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1991-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0384740-A3 |
| titleOfInvention | Method of testing the effect of a molecule on b lymphocyte function |
| abstract | A method of testing the effect of an agonist or nan antagonist to B lymphocyte cell surface protein CD20 nin B lymphocyte function which involves determining ncalcium ion flux across the B lymphocyte membrane, ncontacting the B lymphocyte with the agonist or nantagonist, and determining the change in calcium ion nflux across the membrane after exposure of the B nlymphocyte to the agonist or antagonist, is described. nIn preferred embodiments of the method the agonist or nantagonist is a ligand that binds CD20 or an antibody to nCD20. n In other preferred embodiments, calcium ion nflux is more preferably determined in terms of ntransmembrane current flow and most preferrably ndetermined in terms of the change in cytosolic Ca²⁺ nconcentration. |
| priorityDate | 1989-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 15.