abstract |
The compounds of the formula wherein A represents 6-amino-9H-purin-9-yl or 2-amino-6-hydroxy-9H-purin-9-yl, in which the amino group can be replaced by NHC (O) R² or N = CHR³R⁴ and R OH or OC (O) R¹, where R¹, R², R³ and R⁴ independently of one another straight-chain or branched C₁₋₂₀ alkyl, C₁₋₁₂ alkoxyalkyl, substituted or unsubstituted phenoxy-C₁₋₄-alkyl, phenyl or phenyl by halogen , C₁₋₄-alkoxy, nitro, hydroxy, carboxyl or alkylamino is substituted, and pharmaceutically acceptable salts thereof are of value as agents for the treatment of retroviral infections, such as HIV. |