| abstract |
Compounds of structure (1):n and pharmaceutically acceptable salts are described, wherein nR is hydrogen or C₁₋₄alkyl, nR′ is hydrogen, C₁₋₄alkyl, or a C₁₋₄alkyl group substituted by an alkyne or allene group provided that R′ is not methyl when R and R˝ are both hydrogen, and nR˝ is hydrogen or a C₁₋₄alkyl group substituted by an alkyne or allene group. n These compounds have anti-depressant activity. Processes for the preparation of the compounds, pharmaceutical compositions and methods of use, are described. |